🔗 Effect of Acute Antidepressant Administration on Negative Affective Bias in Depressed Patients -- Harmer et al. 166 (10): 1178 -- Am J Psychiatry
To establish the effects of depression per se, each task was first analyzed for the placebo-treated participants alone by group (depressed patients versus comparison subjects) as the between-subjects factor. For performance in the emotional categorization task and memory, valence (positive or negative) was an additional within-subjects factor. Next, the effects of the drug manipulation were assessed using analysis of variance with drug treatment (reboxetine or placebo) and group (depressed patients or comparison subjects) as between-subjects factors and emotion (positive or negative) as the within-subjects factor, as above. Statistically significant interactions were followed up with simple analyses for group differences.